Description

o-(2-Aminoethyl)-5Z,8Z,11Z,14Z-Eicosatetraenoate is a specialized eicosatetraenoate derivative featuring a terminal aminoethyl group, making it a valuable bifunctional intermediate for chemical synthesis. This compound is particularly significant for researchers and manufacturers developing bioactive molecules, as it combines the structural framework of a polyunsaturated fatty acid with a reactive amine handle. It is primarily utilized in pharmaceutical research, biochemical studies, and the synthesis of complex lipids and conjugates for targeted applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting inflammatory pathways or lipid-mediated signaling.
• Bioconjugation & Probe Development: The amine group enables coupling to fluorescent dyes, affinity tags, or other bioactive molecules for creating research tools and diagnostic probes.
• Lipidomics Research: Used as a reference standard or a synthetic precursor in the study of eicosanoid metabolism and polyunsaturated fatty acid derivatives.
• Biomaterial Functionalization: Employed to introduce lipid-like properties and reactive sites onto polymer backbones or nanoparticle surfaces for enhanced biocompatibility.
• Chemical Biology: Serves as a substrate or inhibitor in enzymatic studies related to lipid-modifying enzymes.
• Cosmeceutical R&D: Investigated for potential use in advanced skincare formulations due to its structural similarity to bioactive lipids.

Basic Information

Product Name	o-(2-Aminoethyl)-5Z,8Z,11Z,14Z-Eicosatetraenoate
CAS No.	287937-12-6
Molecular Formula	C22H37NO2
Molecular Weight	347.54 g/mol
Synonyms	5Z,8Z,11Z,14Z-Eicosatetraenoic Acid 2-Aminoethyl Ester; 2-Aminoethyl Arachidonate (all-Z)-; Arachidonic Acid 2-Aminoethyl Ester; 2-Aminoethyl (5Z,8Z,11Z,14Z)-Eicosatetraenoate; AA-AE; Arachidonoyl Ethanolamine Precursor; Ethanolamine Arachidonate
EINECS	Contact for details

Quality Control

Our production of o-(2-Aminoethyl)-5Z,8Z,11Z,14Z-Eicosatetraenoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic and should be handled in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isomeric Purity (Z-configuration)	≥ 98% (by GC or HPLC)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.