Description

Rostaporfin CAS NO 284041-10-7 is a synthetic chlorin-based photosensitizer developed for photodynamic therapy (PDT) applications. This compound is a key active pharmaceutical ingredient (API) designed for targeted activation by light to treat specific medical conditions. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in developing advanced oncological and dermatological therapies. Its precise mechanism offers a promising approach for selective treatment modalities.

Application

• Photodynamic Therapy (PDT) Agent: As a core photosensitizer in the development of treatments for various cancers, including skin, head, neck, and bladder malignancies.
• Ophthalmological Research: Investigation for use in treating age-related macular degeneration (AMD) and other choroidal neovascularization disorders.
• Dermatology: Potential application in the treatment of actinic keratosis, psoriasis, and other proliferative skin conditions.
• Antimicrobial PDT: Research into its efficacy for localized antimicrobial treatments against drug-resistant bacteria and fungi.
• Pharmaceutical Intermediate: Serves as a critical building block for synthesizing more complex targeted therapeutic conjugates.
• Clinical & Pre-clinical Research: Used in academic and industrial R&D settings to study photodynamic mechanisms and optimize treatment protocols.

Basic Information

Product Name	Rostaporfin
CAS No.	284041-10-7
Molecular Formula	C₅₀H₆₈N₈O₈
Molecular Weight	909.1 g/mol
Synonyms	Motexafin Lutetium; Lu-Tex; Lutetium Texaphyrin; PCI-0123; ANTRIN; Optrin; Lutetium(III) texaphyrin; Rostaporfin (USAN); Texaphyrin Lutetium Complex
EINECS	Contact for details

Quality Control

Our Rostaporfin is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods (IR, NMR), to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) with detailed batch-specific data are provided to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. Due to its hygroscopic nature, the container should be sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent moisture absorption and degradation. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Dark green to black solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Single Largest Unknown Impurity	≤ 1.0%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.