Description

n-((Rs)-2-Hydroxy-1-Phenyl-Ethyl)-Val-Leu-Anilide CAS NO 283159-27-3 is a specialized chiral peptide derivative, designed for advanced research and development applications. This compound serves as a critical building block or intermediate in the synthesis of complex molecules, offering high stereochemical purity and structural specificity. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and fine chemical manufacturers focused on developing novel therapeutic agents, enzyme inhibitors, or chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate peptide-protein interactions.
• Peptide Synthesis: Serves as a protected dipeptide building block (Val-Leu) with a chiral auxiliary for solid-phase or solution-phase peptide synthesis.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Asymmetric Catalysis: Potential use as a ligand or precursor for chiral catalysts in asymmetric synthesis.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	n-((Rs)-2-Hydroxy-1-Phenyl-Ethyl)-Val-Leu-Anilide
CAS No.	283159-27-3
Molecular Formula	C25H33N3O3
Molecular Weight	423.55 g/mol
Synonyms	N-[(1R)-2-Hydroxy-1-phenylethyl]-L-valyl-N-phenyl-L-leucinamide; (R)-N-(2-Hydroxy-1-phenylethyl)-Val-Leu-anilide; Val-Leu-Anilide derivative; Chiral Val-Leu dipeptide anilide; L-Valyl-N-[(1R)-2-hydroxy-1-phenylethyl]-N-phenyl-L-leucinamide; Peptide anilide intermediate; CAS 283159-27-3
EINECS	Contact for details

Quality Control

Our n-((Rs)-2-Hydroxy-1-Phenyl-Ethyl)-Val-Leu-Anilide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research applications. A detailed Certificate of Analysis (COA) providing batch-specific results for identity, purity, and related substances is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.