Description

1-Myristoyl-2-(4-Nitrophenylsuccinyl)-Sn-Glycero-3-Phosphocholine is a synthetic, chemically modified phospholipid designed for advanced research and development applications. This compound is engineered to serve as a critical tool in membrane biophysics and pharmaceutical formulation studies, offering precise structural control. It is primarily utilized by researchers and product developers in the life sciences, pharmaceutical, and specialty chemical industries for creating model membrane systems and investigating drug delivery mechanisms.

Application

• Membrane Biophysics Research: Used as a key component in the construction of artificial lipid bilayers and vesicles (liposomes) to study membrane fluidity, permeability, and protein-lipid interactions.
• Drug Delivery System Development: Acts as a functionalized lipid in the formulation of targeted liposomal carriers, where the 4-nitrophenylsuccinyl moiety can be utilized for further conjugation with active pharmaceutical ingredients or targeting ligands.
• Biochemical Probe: Serves as a substrate or inhibitor in enzymatic studies related to phospholipase activity and lipid metabolism pathways.
• Pharmaceutical R&D: Employed in pre-formulation studies to understand the stability and behavior of complex lipid-based formulations under various conditions.
• Diagnostic Reagent Component: Can be incorporated into diagnostic assays and kits that rely on lipid membrane structures for signal generation or capture.

Basic Information

Product Name	1-Myristoyl-2-(4-Nitrophenylsuccinyl)-Sn-Glycero-3-Phosphocholine
CAS No.	273931-53-6
Molecular Formula	C₃₃H₅₅N₂O₁₂P
Molecular Weight	702.77 g/mol
Synonyms	1-Myristoyl-2-(4-Nitrophenylsuccinyl)-Sn-Glycero-3-Phosphocholine; 1-Myristoyl-2-[4-(3-carboxypropanoyl)nitrophenyl]-sn-glycero-3-phosphocholine; NPS-PC; 4-Nitrophenylsuccinyl Phosphatidylcholine; PNPS-PC; 1-Myristoyl-2-(4-NPS)-sn-Glycero-3-PC; Modified Phosphatidylcholine Derivative; CAS 273931-53-6
EINECS	Contact for details

Quality Control

Our 1-Myristoyl-2-(4-Nitrophenylsuccinyl)-Sn-Glycero-3-Phosphocholine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing specific test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.