Description

n-(3-Hydroxy-7-Cis Tetradecenoyl)-L-Homoserine Lactone is a specialized N-acyl homoserine lactone (AHL) signaling molecule. This compound is of significant interest for its role in mediating quorum sensing, a key bacterial communication process that regulates gene expression based on population density. It is primarily utilized by researchers and developers in the fields of microbiology, biotechnology, and pharmaceutical discovery to study and potentially control bacterial behavior, including biofilm formation and virulence.

Application

• Quorum Sensing Research: A critical tool for studying intercellular signaling in Gram-negative bacteria, particularly in the development of anti-virulence strategies.
• Biofilm Studies: Used to investigate and modulate the formation of bacterial biofilms, which are relevant to medical device infections and industrial biofouling.
• Microbial Ecology: Employed to understand population dynamics and symbiotic or pathogenic interactions within microbial communities.
• Pharmaceutical Screening: Serves as a reference standard or active component in high-throughput screens for novel quorum sensing inhibitors (QSIs) and anti-infective agents.
• Agricultural Biotechnology: Applied in research aimed at disrupting pathogenic bacterial communication in crops to develop alternative plant protection methods.
• Academic & Institutional Research: Essential reference material for universities and research institutes conducting fundamental studies in bacterial physiology and synthetic biology.

Basic Information

Product Name	n-(3-Hydroxy-7-Cis Tetradecenoyl)-L-Homoserine Lactone
CAS No.	273734-65-9
Molecular Formula	C18H31NO4
Molecular Weight	325.45 g/mol
Synonyms	N-[(3S)-3-Hydroxytetradec-7-enoyl]-L-homoserine lactone; 3-Hydroxy-C14:1-δ7-cis-HSL; N-(3-Hydroxy-cis-7-tetradecenoyl)homoserine lactone; C14-HSL (3-hydroxy, cis-7); AHL C14:1 (3-OH); Bacterial Quorum Sensing Molecule C14; N-Acyl Homoserine Lactone Signal; Contact for EINECS details.

Quality Control

Our n-(3-Hydroxy-7-Cis Tetradecenoyl)-L-Homoserine Lactone is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for high-purity research chemicals, ensuring material integrity for sensitive biological assays.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.