Description

2-Cyclohexylethyl-β-D-Maltoside is a high-purity, non-ionic surfactant and detergent belonging to the maltoside family, specifically designed for demanding biochemical and biophysical research applications. Its unique structure, featuring a cyclohexylethyl hydrophobic tail, provides superior stability and performance in solubilizing and stabilizing membrane proteins compared to more common alkyl maltosides. This compound is essential for researchers and process developers in structural biology, pharmaceutical development, and advanced material sciences who require reliable, high-quality reagents for challenging protein work.

Application

• Membrane Protein Solubilization & Stabilization: Critical for extracting and maintaining the native conformation of integral membrane proteins from cellular membranes for structural and functional studies.
• Structural Biology: Used in the purification and crystallization of membrane proteins for X-ray crystallography and cryo-electron microscopy (cryo-EM) analysis.
• Biophysical Characterization: Employed in techniques such as surface plasmon resonance (SPR), isothermal titration calorimetry (ITC), and nuclear magnetic resonance (NMR) to study protein-ligand interactions in a membrane-like environment.
• Vaccine & Therapeutic Development: Serves as a key excipient in the formulation of vaccines and biologics that target membrane-bound antigens.
• Liposome & Nanodisc Preparation: Facilitates the formation and loading of model membrane systems used for drug delivery and in vitro assays.
• Diagnostic Assays: Used as a stabilizing agent in diagnostic kits and reagents that involve membrane-bound enzymes or receptors.

Basic Information

Product Name	2-Cyclohexylethyl-β-D-Maltoside
CAS No.	260804-65-7
Molecular Formula	C20H36O11
Molecular Weight	452.50 g/mol
Synonyms	2-Cyclohexylethyl β-D-maltoside; Cyclohexylethyl-β-D-maltopyranoside; CHM; Cymal-6 (common trade name analog); 2-(Cyclohexyl)ethyl β-maltoside; Heptakis(2,6-di-O-methyl)-β-cyclodextrin (related compound); Maltose, 2-cyclohexylethyl β-D-; Non-ionic detergent CHM.
EINECS	Contact for details

Quality Control

Every batch of 2-Cyclohexylethyl-β-D-Maltoside is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for life science research. Our quality protocols include identity confirmation, purity assay, and critical impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with our rigorous specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Critical Micelle Concentration (CMC)	Contact for details
Bacterial Endotoxins	< 0.25 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.