Description

Ac-Arg-Ser-Leu-Lys-Amc CAS NO 259176-76-6 is a synthetic, fluorogenic peptide substrate designed for high-sensitivity enzymatic assays. This compound is critical for researchers and quality control laboratories requiring precise measurement of specific protease activity. It is primarily utilized in biochemical research, pharmaceutical development, and diagnostic applications where accurate enzyme kinetics are paramount.

Application

• Protease Activity Assays: Used as a selective substrate for measuring the activity of specific proteolytic enzymes, including trypsin-like serine proteases.
• Biochemical Research: Enables kinetic studies and characterization of enzyme mechanisms, inhibition, and activation in vitro.
• Drug Discovery & Development: Facilitates high-throughput screening (HTS) for identifying and optimizing novel protease inhibitors as therapeutic candidates.
• Diagnostic Reagent Manufacturing: Serves as a key component in the formulation of diagnostic kits for clinical and research use.
• Quality Control (QC) Testing: Employed in biopharmaceutical QC to monitor and validate the purity and activity of enzyme-based products.

Basic Information

Product Name	Ac-Arg-Ser-Leu-Lys-Amc
CAS No.	259176-76-6
Molecular Formula	C32H53N11O9
Molecular Weight	735.84 g/mol
Synonyms	Acetyl-Arg-Ser-Leu-Lys-7-amido-4-methylcoumarin; Ac-Arg-Ser-Leu-Lys-AMC; Ac-RSLK-AMC; Ac-RSLK-AMC Fluorogenic Substrate; N-Acetyl-L-arginyl-L-seryl-L-leucyl-L-lysyl-7-amido-4-methylcoumarin; Protease Substrate 259176-76-6; Fluorogenic Peptide Substrate for Protease
EINECS	Contact for details

Quality Control

Our Ac-Arg-Ser-Leu-Lys-Amc is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.