Description

C2 3'-Sulfo Galactosylceramide (D18:1/2:0) is a specific, high-purity sulfoglycolipid derivative, also known as a sulfatide analog, with the CAS number 252846-08-5. This compound is a critical biochemical tool for studying lipid metabolism, cell signaling, and the role of sulfatides in neurological and immunological processes. It is essential for researchers and developers in pharmaceutical R&D, diagnostic assay development, and advanced biochemical synthesis requiring well-defined lipid standards and intermediates.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in lipidomics and metabolomics studies to identify and quantify sulfatides in biological samples.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the development of therapies targeting lysosomal storage disorders or neuroinflammatory conditions.
• Diagnostic Reagent Formulation: Employed in the development of diagnostic kits and assays for enzymes like arylsulfatase A, relevant for diagnosing conditions like metachromatic leukodystrophy (MLD).
• Cell Biology & Signaling Studies: Utilized to investigate the role of sulfatides in cell membrane structure, protein-lipid interactions, and immune cell modulation.
• Lipidomics Calibration: Acts as a critical calibration standard for mass spectrometry (MS) and high-performance liquid chromatography (HPLC) methods in analytical laboratories.
• Enzyme Activity Assays: Functions as a specific substrate for in vitro enzymatic assays to study sulfatase activity and inhibition.

Basic Information

Product Name	C2 3'-Sulfo Galactosylceramide (D18:1/2:0)
CAS No.	252846-08-5
Molecular Formula	C₂₆H₄₉NO₁₀S
Molecular Weight	567.7 g/mol
Synonyms	3'-Sulfo-D-galactosylceramide (C2); Sulfatide (C2); 3-O-Sulfo-β-D-galactosylceramide (D18:1/2:0); N-Acetyl-3'-sulfogalactosylsphingosine; C2-Sulfatide; Galactosylceramide sulfate (C2); 1-O-(3-O-Sulfo-β-D-galactopyranosyl)-N-acetylsphingosine; Cerebroside sulfuric ester (C2)
EINECS	Contact for details

Quality Control

Our C2 3'-Sulfo Galactosylceramide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, MS, and NMR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.