Description

Rac Formoterol 1'-o-β-D-Glucuronide is a key glucuronide metabolite of the bronchodilator formoterol. This compound is of significant importance for pharmaceutical research and development, particularly in the study of drug metabolism, pharmacokinetics, and bioanalytical method validation. It serves as a critical reference standard for laboratories in the pharmaceutical, contract research organization (CRO), and academic sectors requiring precise analytical tools for metabolite identification and quantification.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the calibration of analytical instruments and validation of bioanalytical methods.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Essential for investigating the metabolic pathways, clearance mechanisms, and bioavailability of formoterol and related compounds.
• Bioanalytical Assay Development: Used as a standard to develop and optimize High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS/MS) assays in biological matrices.
• Toxicology and Safety Assessment: Employed in studies to understand the safety profile and potential toxicity of formoterol metabolites.
• Quality Control in API Manufacturing: Supports impurity profiling and ensures the quality and consistency of active pharmaceutical ingredient (API) batches.
• Academic and Clinical Research: Facilitates fundamental research into respiratory therapeutics and the role of glucuronidation in drug action.

Basic Information

Product Name	Rac Formoterol 1'-o-β-D-Glucuronide
CAS No.	250336-07-3
Molecular Formula	C25H37NO9
Molecular Weight	495.57 g/mol
Synonyms	Formoterol 1'-O-β-D-Glucuronide; (Rac)-Formoterol 1'-O-β-D-Glucuronide; 1'-O-(β-D-Glucopyranuronosyl)formoterol; Formoterol Glucuronide; Formoterol 1'-Glucuronide; (±)-Formoterol 1'-O-β-D-Glucuronide; 250336-07-3; N-[2-Hydroxy-5-[(1RS)-1-hydroxy-2-[[(1RS)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide 1'-O-β-D-glucopyranosiduronic acid
EINECS	Contact for details

Quality Control

Our Rac Formoterol 1'-o-β-D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity assay, chiral purity determination, and identity confirmation (IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	Contact for details
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.