Description

1 2-Dioleoyl-Sn-Glycero-3-Phospho-L-Seri is a high-purity, synthetic phospholipid derivative, specifically a phosphatidylserine (PS) species with oleoyl fatty acid chains. This compound is a critical functional component in the formulation of advanced lipid-based delivery systems, where it contributes to membrane stability and bio-recognition. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries developing liposomal drug carriers, diagnostic agents, and specialized supplements.

Application

• Liposomal Drug Delivery: A key excipient for creating stable, long-circulating, and target-specific liposomes for cancer therapeutics, vaccines, and gene therapy.
• Biomimetic Membrane Research: Used to construct model cell membranes (e.g., supported lipid bilayers, vesicles) for studying membrane-protein interactions, signaling, and fusion processes.
• Diagnostic Formulations: Incorporated into contrast agents for medical imaging (e.g., ultrasound, MRI) and as a component in assay kits.
• Cognitive Health Supplements: Serves as a reference standard or a high-grade raw material in the production of phosphatidylserine-based nutraceuticals.
• Cell Culture & Cryopreservation: Enhances cell membrane integrity and viability in specialized cell culture media and cryoprotectant solutions.
• Cosmetic Actives Delivery: Used in premium cosmetic formulations to improve the skin penetration and stability of active ingredients.

Basic Information

Product Name	1 2-Dioleoyl-Sn-Glycero-3-Phospho-L-Seri
CAS No.	245665-28-5
Molecular Formula	C45H82NO10P
Molecular Weight	828.11 g/mol
Synonyms	DOPS; 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine; L-α-Phosphatidylserine (dioleoyl); 1,2-Di-O-octadecenoyl-sn-glycero-3-phospho-L-serine; (2S)-2-Amino-3-({[(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy](hydroxy)phosphoryl}oxy)propanoic acid; Phosphatidylserine (18:1); PS(18:1/18:1); OOPS
EINECS	Contact for details

Quality Control

Our 1 2-Dioleoyl-Sn-Glycero-3-Phospho-L-Seri is manufactured under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and consistency suitable for research and cGMP applications. Comprehensive analytical methods including HPLC, NMR, and MS are employed. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0% (Area %)
Solubility	Soluble in chloroform, ethanol; forms liposomes in aqueous buffer
Heavy Metals	< 10 ppm
Residual Solvents	Meets ICH guidelines
Microbial Limits	< 100 CFU/g (Total Aerobic Microbial Count)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.