Description

C18 3'-Sulfo Galactosylceramide (D18:1/18:0) is a high-purity, well-defined sulfoglycolipid, specifically a sulfatide, with the CAS number 244215-65-4. This compound is a critical reagent in lipidomics research and the development of diagnostic tools, serving as a key standard for the identification and quantification of sulfatides in biological samples. It is essential for researchers and manufacturers in the fields of biochemistry, neuroscience, and in vitro diagnostics who require structurally precise lipids for analytical method development, biomarker discovery, and quality control.

Application

• Biomarker Research & Diagnostic Development: Used as a primary standard for the detection and quantification of sulfatides in plasma, serum, and cerebrospinal fluid, aiding in the study of metabolic disorders like metachromatic leukodystrophy (MLD).
• Lipidomics & Metabolomics: A critical reference compound for mass spectrometry (LC-MS/MS, MALDI-TOF) and chromatographic (HPLC) platforms to validate analytical methods and create calibration curves.
• Neuroscience & Cell Biology: Employed in studies of myelin formation, lysosomal storage diseases, and the role of sulfatides in cell signaling, membrane structure, and neural function.
• Pharmaceutical R&D: Serves as a substrate or target molecule in high-throughput screening assays for drug discovery programs focused on lysosomal enzymes or lipid metabolism pathways.
• In Vitro Diagnostic (IVD) Manufacturing: Incorporated as a calibrator or control in diagnostic kits designed to measure enzyme activity (e.g., arylsulfatase A) or specific lipid biomarkers.
• Biochemical Reagent: Used for the preparation of liposomes, lipid bilayers, and other model membrane systems to study lipid-protein interactions.

Basic Information

Product Name	C18 3'-Sulfo Galactosylceramide (D18:1/18:0)
CAS No.	244215-65-4
Molecular Formula	C42H81NO11S
Molecular Weight	808.17 g/mol
Synonyms	Sulfatide (D18:1/18:0); 3-O-Sulfo-β-D-galactosylceramide (D18:1/18:0); Cerebroside sulfuric ester; Galactosylceramide sulfate; SM4s; Sulfogalactosylceramide; N-(Octadecanoyl)-1-β-D-galactosyl-sphing-4-enine-1,3-diyl hydrogen sulfate; N-Stearoyl Sulfatide
EINECS	Contact for details

Quality Control

Our C18 3'-Sulfo Galactosylceramide is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive research and diagnostic applications. Each lot is characterized using advanced analytical techniques including NMR, Mass Spectrometry (MS), and High-Performance Liquid Chromatography (HPLC). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 98% (by weight)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in chloroform/methanol mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.