Description

4-Methylumbelliferyl Myo-Inositol 1-Phosphate Lithium Salt is a high-purity fluorogenic substrate specifically designed for enzymatic assays. This compound is critical for the sensitive and quantitative detection of inositol monophosphatase and related phosphatase activities in biochemical research. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, diagnostic, and life science sectors, enabling the study of cellular signaling pathways and the screening of therapeutic compounds.

Application

• Enzymatic Substrate for Inositol Monophosphatase (IMPase): Primary fluorogenic substrate for kinetic studies and inhibition assays of IMPase, a key enzyme in the phosphatidylinositol signaling pathway.
• High-Throughput Screening (HTS): Used in automated assay platforms for the discovery and development of novel therapeutics targeting bipolar disorder and neurological conditions.
• Biochemical Research & Diagnostics: Essential for fundamental research into lithium's mechanism of action and for developing diagnostic methods related to inositol metabolism.
• Pharmaceutical Quality Control: Employed in potency testing and stability studies of drug products where IMPase activity is a relevant metric.
• Enzyme Characterization: Facilitates the determination of kinetic parameters (Km, Vmax) and pH optima for phosphatases that recognize this specific substrate.

Basic Information

Product Name	4-Methylumbelliferyl Myo-Inositol 1-Phosphate Lithium Salt
CAS No.	244145-22-0
Molecular Formula	C16H17LiO11P
Molecular Weight	399.21 g/mol
Synonyms	4-MU-Inositol 1-Phosphate Li Salt; 4-Methylumbelliferyl-α-D-myo-Inositol 1-Phosphate Lithium Salt; Fluorogenic Inositol Monophosphatase Substrate; 4-MU-Ins-1-P Li; 1D-myo-Inositol 1-(4-Methylumbelliferyl phosphate) Lithium Salt; IMPase Substrate; Inositol Monophosphatase Fluorogenic Substrate
EINECS	Contact for details

Quality Control

Every batch of our 4-Methylumbelliferyl Myo-Inositol 1-Phosphate Lithium Salt is manufactured and tested to meet stringent standards for research and diagnostic use. Our quality assurance protocol includes comprehensive analytical testing to ensure high purity, correct identity, and optimal performance in fluorogenic assays. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and assay is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 105.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Fluorogenic Activity	Functional in standard IMPase assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.