Description

n-Biotinyl Dopamine is a specialized biochemical conjugate that combines the neurotransmitter dopamine with the essential vitamin biotin. This compound is critical for advanced research in neuroscience and molecular biology, enabling targeted studies of dopaminergic systems. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic developers working on neurochemical pathways, receptor mapping, and targeted drug delivery mechanisms.

Application

• Neurochemical Research: As a biotinylated probe for studying dopamine receptors, transporters, and signaling pathways in vitro and in vivo.
• Affinity Purification: Used to isolate and purify dopamine-binding proteins or receptors via streptavidin/avidin-biotin interaction.
• Diagnostic Assay Development: Serves as a key component in the development of ELISA, immunohistochemistry (IHC), or other bioanalytical tests for neurological markers.
• Targeted Drug Delivery Systems: Investigated as a potential targeting ligand in conjugate therapeutics for neurological disorders.
• Bioconjugation & Labeling: Acts as a versatile intermediate for creating labeled dopamine analogs for imaging and detection.
• High-Throughput Screening (HTS): Employed in assay development for screening compound libraries against dopaminergic targets.

Basic Information

Product Name	n-Biotinyl Dopamine
CAS No.	241142-94-9
Molecular Formula	C19H27N5O4S
Molecular Weight	421.51 g/mol
Synonyms	Biotin-Dopamine; Biotinylated Dopamine; Dopamine-Biotin Conjugate; N-((3,4-Dihydroxyphenethyl)carbamoyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; 5-[(3aS,4S,6aR)-2-Oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-(3,4-dihydroxyphenyl)ethyl]pentanamide
EINECS	Contact for details

Quality Control

Our n-Biotinyl Dopamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.