Description

D-Ribo-Phytosphingosine-13C2,D2 is a high-purity, isotopically labeled derivative of phytosphingosine, a key bioactive sphingolipid backbone. This stable isotope-labeled compound is essential for advanced analytical research, enabling precise metabolic tracing and quantification in complex biological systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug development, biomarker discovery, and lipidomics.

Application

• As an internal standard for the accurate quantification of endogenous phytosphingosine and related sphingolipids via LC-MS/MS and GC-MS.
• For metabolic pathway tracing studies to elucidate the biosynthesis and turnover of sphingolipids in cell culture and model organisms.
• In pharmaceutical R&D for investigating the role of sphingolipid signaling in disease mechanisms and therapeutic interventions.
• Use in cosmeceutical research to study the effects of phytosphingosine on skin barrier function and ceramide production.
• As a critical reagent in the development and validation of clinical diagnostic assays for sphingolipid-related disorders.
• For biochemical research involving enzyme kinetics and inhibition studies of sphingolipid-metabolizing enzymes.

Basic Information

Product Name	D-Ribo-Phytosphingosine-13C2,D2
CAS No.	237757-10-7
Molecular Formula	C1813C2H35D2NO4
Molecular Weight	Contact for details
Synonyms	(2S,3S,4R)-2-Amino-1,3,4-octadecanetriol-13C2,D2; Phytosphingosine-13C2,D2; D-ribo-1,3,4-Trihydroxy-2-aminooctadecane-13C2,D2; 4-Hydroxysphinganine-13C2,D2; 4-Hydroxy-D-erythro-sphinganine-13C2,D2; TMS-0 Phytosphingosine-13C2,D2; C18 Phytosphingosine-13C2,D2; D-erythro-Phytosphingosine-13C2,D2
EINECS	Contact for details

Quality Control

Every batch of D-Ribo-Phytosphingosine-13C2,D2 is manufactured and analyzed under strict quality systems. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and identity is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic and oxidatively sensitive nature, the product should be handled in a dry, controlled environment and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity	≥ 98 atom % 13C; ≥ 98 atom % D
Chemical Purity	≥ 98%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.