Description

Trt-Peg4-Otos CAS NO 223611-40-3 is a specialized heterobifunctional PEG linker featuring a trityl (Trt) protecting group and a tosylate (Otos) leaving group, connected by a tetraethylene glycol (Peg4) spacer. This compound is engineered for controlled bioconjugation and polymer synthesis, offering precise reactivity for attaching molecules to surfaces or other biomolecules. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, proteomics, and advanced material science for creating targeted drug delivery systems, diagnostic probes, and functionalized polymers.

Application

• Bioconjugation Reagent: Used for the site-specific modification of peptides, proteins, and antibodies in drug development.
• Polymer Chemistry: Serves as a functional initiator or monomer in the synthesis of PEGylated polymers and hydrogels.
• Probe Synthesis: Facilitates the creation of fluorescent or affinity-labeled probes for diagnostic and imaging applications.
• Surface Functionalization: Enables the controlled attachment of biomolecules to nanoparticles, chips, and other solid supports.
• Linker for Solid-Phase Synthesis: Employed in peptide and oligonucleotide synthesis as a cleavable, protected linker.
• Cross-linking Agent: Used to create stable cross-links between molecules in material science and biotech applications.

Basic Information

Product Name	Trt-Peg4-Otos
CAS No.	223611-40-3
Molecular Formula	C38H52O8S
Molecular Weight	668.88 g/mol
Synonyms	Trityl-PEG4-tosylate; 2,5,8,11-Tetraoxatridecan-13-yl 4-methylbenzenesulfonate, Trityl Derivative; 4-Methylbenzenesulfonic Acid Trityl-PEG4 Ester; Monomethoxytrityl-PEG4-OTs; MMTr-PEG4-OTs; Trt-O-(CH2CH2O)4-OTs; Trt-PEG4-OTs; (Triphenylmethyl)tetraethylene glycol tosylate
EINECS	Contact for details

Quality Control

Every batch of Trt-Peg4-Otos undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for research and production. Our quality assurance includes HPLC, NMR, and mass spectrometry analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.