Description

Tigecycline CAS NO 220620-09-7 is a broad-spectrum glycylcycline antibiotic derived from minocycline. It is a critical pharmaceutical active ingredient valued for its efficacy against multidrug-resistant pathogens, including methicillin-resistant *Staphylococcus aureus* (MRSA) and vancomycin-resistant enterococci (VRE). This compound is essential for the formulation of injectable antibiotics used in clinical settings to treat complicated skin, skin structure, and intra-abdominal infections. Pharmaceutical manufacturers and research institutions globally rely on high-purity tigecycline for drug development and production.

Application

• Pharmaceutical API: Primary use as the active pharmaceutical ingredient (API) in injectable antibiotic formulations.
• Hospital-Acquired Infection Treatment: Key component in drugs targeting complicated intra-abdominal infections (cIAI) and complicated skin and skin structure infections (cSSSI).
• Antibiotic Research: A vital reference standard and intermediate in antimicrobial resistance (AMR) research and the development of novel tetracycline-class antibiotics.
• Veterinary Medicine: Investigational use in veterinary pharmaceuticals for treating serious bacterial infections in animals.
• Microbiological Media: Used in selective culture media for laboratory studies of antibiotic susceptibility and bacterial genetics.

Basic Information

Product Name	Tigecycline
CAS No.	220620-09-7
Molecular Formula	C29H39N5O8
Molecular Weight	585.65 g/mol
Synonyms	(9-t-Butylglycylamido-minocycline); GAR-936; Tygacil (Brand Name); (4S,4aS,5aR,12aS)-9-[2-(tert-Butylamino)acetamido]-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide; Wyeth 220620-09-7; Antibiotic GAR 936
EINECS	Contact for details

Quality Control

Our Tigecycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and support regulatory filings. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with every shipment, confirming compliance with in-house specifications aligned with major pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F), or under the conditions specified on the label. The product is light-sensitive and should be stored away from light. Keep the container tightly sealed in a dry environment to protect the hygroscopic material.

Specification

Item	Specification
Appearance	Yellow to orange amorphous powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Specific Optical Rotation	-15° to -25° (c=1 in DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.