Description

Ac-Veid-Amc is a specialized peptide compound, identified by CAS NO 219137-97-0, that serves as a critical substrate and research tool in biochemical studies. Its primary value lies in its role as a selective and sensitive fluorogenic substrate for caspase-6, a key enzyme involved in apoptosis and neurodegenerative pathways. This product is essential for researchers and developers in the fields of pharmaceutical R&D, proteomics, and diagnostic assay development, enabling precise measurement of enzymatic activity and inhibitor screening.

Application

• Caspase-6 Activity Assays: Primary fluorogenic substrate for in vitro enzymatic activity studies.
• Apoptosis Research: Used to detect and quantify caspase-6 activation during programmed cell death.
• Drug Discovery & Screening: High-throughput screening of potential caspase-6 inhibitors for therapeutic development.
• Neurodegenerative Disease Models: Research tool in studying diseases like Alzheimer's and Huntington's where caspase-6 plays a role.
• Biochemical Reagent: Key component in research kits for studying protease function and signaling pathways.
• Academic & Institutional Research: Fundamental tool for universities and research institutes in cell biology and biochemistry.

Basic Information

Product Name	Ac-Veid-Amc
CAS No.	219137-97-0
Molecular Formula	C27H38N6O9
Molecular Weight	590.63 g/mol
Synonyms	Ac-Val-Glu-Ile-Asp-AMC; Ac-VEID-AMC; Ac-VEID-7-amido-4-methylcoumarin; Caspase-6 Substrate I; Caspase-6 Fluorogenic Substrate; N-Acetyl-Val-Glu-Ile-Asp-7-amido-4-methylcoumarin; Ac-DEVD-AMC Analog; Apoptosis Substrate V
EINECS	Contact for details

Quality Control

Our Ac-Veid-Amc is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assay conditions. We adhere to ISO 9001 quality management principles, and our production environment is designed to prevent cross-contamination, ensuring reliable results for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF
Functional Activity (Assay)	Conforms to reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.