Description

(±)14(15)-Eet-Si CAS NO 218461-97-3 is a specialized epoxide derivative of eicosatetraenoic acid (EET), a key signaling molecule in the cytochrome P450 pathway. This compound is of significant value for researchers investigating the complex roles of EETs and their metabolites in cardiovascular, renal, and inflammatory processes. It serves as a critical reference standard and synthetic intermediate for pharmaceutical R&D, analytical method development, and biochemical studies in the life sciences sector.

Application

• Biochemical Research: Used as a reference standard and probe to study the biological activity, metabolism, and signaling pathways of epoxyeicosatrienoic acids (EETs).
• Pharmaceutical Development: Acts as a key synthetic intermediate or precursor in the discovery and development of novel therapeutics targeting cardiovascular diseases, hypertension, and inflammation.
• Analytical Chemistry: Serves as a high-purity calibration standard for quantitative analysis (e.g., LC-MS, GC-MS) in metabolomics and lipidomics research.
• Enzyme Studies: Utilized as a substrate to investigate the activity and inhibition of soluble epoxide hydrolase (sEH) and other related enzymes.
• Metabolite Identification: Essential for the synthesis and identification of downstream metabolites in eicosanoid research.

Basic Information

Product Name	(±)14(15)-Eet-Si
CAS No.	218461-97-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(±)14,15-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid; (±)14(15)-EET; 14(15)-Epoxy-5,8,11-eicosatrienoic Acid; 14,15-Epoxyeicosa-5,8,11-trienoic Acid; (±)-14,15-EET; 14,15-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid; Arachidonic Acid 14,15-Epoxide; (±)14,15-Epoxyeicosatrienoic Acid
EINECS	Contact for details

Quality Control

Our (±)14(15)-Eet-Si is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity confirmation, and impurity profiles are available upon request to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.