Description

4-Aminomethyl Benzamidine Dihydrochloride is a high-purity, dihydrochloride salt derivative of benzamidine, valued for its potent and specific inhibitory activity against serine proteases. This compound is a critical building block and research reagent in the development of pharmaceutical agents and diagnostic tools. It is primarily needed by research institutions and manufacturers in the life sciences, pharmaceutical, and biotechnology sectors for applications in drug discovery, biochemical research, and assay development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel therapeutic agents, particularly protease inhibitors.
• Biochemical Research: Used as a potent and selective inhibitor for studying serine protease enzymes (e.g., trypsin, thrombin) in enzymatic assays and pathway analysis.
• Diagnostic Reagent Manufacturing: Employed in the formulation of diagnostic kits and reagents that detect or quantify protease activity.
• Peptide Synthesis: Acts as a protecting group or a functional handle in solid-phase and solution-phase peptide chemistry.
• Cell Culture & Microbiology: Utilized in research media and protocols to inhibit specific proteases that may degrade proteins of interest.
• Academic & Contract Research: A fundamental tool for universities and CROs (Contract Research Organizations) conducting basic and applied life science research.

Basic Information

Product Name	4-Aminomethyl Benzamidine Dihydrochloride
CAS No.	217313-79-6
Molecular Formula	C8H12N4 · 2HCl
Molecular Weight	237.12 g/mol
Synonyms	4-(Aminomethyl)benzamidine dihydrochloride; (4-(Aminomethyl)phenyl)methanimidamide dihydrochloride; p-Aminomethylbenzamidine Dihydrochloride; Benzamidine, 4-(aminomethyl)-, dihydrochloride; AMBD HCl; P-AMBA·2HCl
EINECS	Contact for details

Quality Control

Our 4-Aminomethyl Benzamidine Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.