Description

1,2-Di-(9,10-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine is a synthetic, brominated phospholipid derivative, specifically a phosphatidylcholine analog, designed for advanced research and development applications. This compound is valued for its unique chemical structure, which introduces bromine atoms at specific positions on the fatty acid chains, altering its physical and biochemical properties. It is primarily utilized by researchers and product developers in the life sciences, pharmaceutical, and specialty chemical sectors for applications requiring modified lipid behavior, such as in membrane studies, drug delivery systems, and as a specialty intermediate.

Application

• Lipid Membrane Research: Used as a specialized component in model membrane systems (e.g., liposomes, bilayers) to study the effects of bromination on membrane fluidity, permeability, and phase behavior.
• Drug Delivery Vehicle Development: Serves as a functionalized lipid for formulating advanced liposomal or nanoparticle-based carriers, where the bromine groups can be leveraged for further chemical conjugation or to modulate stability.
• Biochemical Probe Synthesis: Acts as a key intermediate or precursor for synthesizing tagged or cross-linkable phospholipids used in proteomics, lipidomics, and cellular trafficking studies.
• Reference Standard: Employed as an analytical standard in quality control and method development for lipid analysis using techniques like HPLC, LC-MS, or NMR.
• Material Science: Investigated for creating novel biomimetic materials or surface coatings with specific hydrophobic and structural characteristics.

Basic Information

Product Name	1,2-Di-(9,10-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine
CAS No.	217075-01-9
Molecular Formula	C46H86Br4NO8P
Molecular Weight	1084.78 g/mol
Synonyms	1,2-Di(9,10-dibromostearoyl)-sn-glycero-3-phosphocholine; 1,2-Bis(9,10-dibromooctadecanoyl)-sn-glycero-3-phosphocholine; Dibromostearoyl Phosphatidylcholine; Br4-PC; 9,10-Dibromo-Stearoyl PC; Brominated DPPC analog; Phosphatidylcholine, 1,2-di(9,10-dibromooctadecanoyl)-, (R)-; L-α-Phosphatidylcholine, 1,2-di(9,10-dibromostearoyl)-
EINECS	Contact for details

Quality Control

Our 1,2-Di-(9,10-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality standards, with testing typically including identification by NMR and mass spectrometry, assay by HPLC, and control of related substances. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid / waxy solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.