Description

Carboxyumbelliferyl β-D-Glucuronide is a high-purity fluorogenic substrate specifically designed for enzymatic assays. This compound is critical for the sensitive and selective detection of β-glucuronidase activity, a key biomarker in various biochemical and diagnostic applications. It is an essential reagent for researchers and manufacturers in the pharmaceutical, biotechnology, and clinical diagnostics industries, enabling advanced research in enzyme kinetics, high-throughput screening, and diagnostic test development.

Application

• Biochemical Research: As a fluorogenic substrate for studying β-glucuronidase enzyme kinetics, inhibition, and characterization.
• Diagnostic Assays: Key component in fluorometric kits for the detection of β-glucuronidase activity, used as an indicator for bacterial contamination (e.g., E. coli) and certain medical conditions.
• Pharmaceutical Screening: Utilized in high-throughput screening (HTS) platforms to identify potential modulators or inhibitors of β-glucuronidase for drug discovery.
• Cell Biology: Used in reporter gene assays and for visualizing enzyme activity within cells and tissues.
• Microbiology: Employed in microbial detection and identification systems that rely on β-glucuronidase as a marker enzyme.
• Quality Control: Serves as a reference standard in the quality control of diagnostic reagents and enzyme preparations.

Basic Information

Product Name	Carboxyumbelliferyl β-D-Glucuronide
CAS No.	216672-17-2
Molecular Formula	C16H16O11
Molecular Weight	384.29 g/mol
Synonyms	4-Methylumbelliferyl-7-β-D-glucuronide; 7-Hydroxy-4-methylcoumarin-7-yl β-D-glucopyranosiduronic acid; 4-MU-β-D-Glucuronide; 4-Methylumbelliferyl β-D-Glucuronide; β-Glucuronidase substrate; 4-MUG; 4-MUGluor; 7-(β-D-Glucopyranosyluronic acid)-4-methylcoumarin
EINECS	Contact for details

Quality Control

Our Carboxyumbelliferyl β-D-Glucuronide is manufactured under strict quality controls to ensure high purity and batch-to-batch consistency suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance data. We adhere to relevant quality management standards to support our global clientele in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Fluorogenic Activity	Conforms to performance standard
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.