Description

5-(Tosyloxyimino)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione is a specialized organic reagent belonging to the class of active ester compounds. It serves as a highly effective acylating agent and coupling reagent, crucial for introducing the tosyloxyimino functional group in complex synthetic sequences. This compound is primarily utilized by pharmaceutical and fine chemical research & development teams for the synthesis of novel drug candidates, heterocyclic compounds, and advanced intermediates.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for constructing complex molecular scaffolds in active pharmaceutical ingredient (API) development.
• Peptide Coupling Reagent: Facilitates amide bond formation in peptide synthesis as an active ester derivative.
• Polymer Chemistry: Used in the modification and functionalization of polymers to introduce specific reactive sites.
• Agrochemical Research: Intermediate in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the surface modification of materials and the creation of specialty coatings.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	5-(Tosyloxyimino)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione
CAS No.	215436-24-1
Molecular Formula	C13H13NO7S
Molecular Weight	327.31 g/mol
Synonyms	5-[(4-Methylphenyl)sulfonyl]oxyimino-2,2-dimethyl-1,3-dioxane-4,6-dione; 2,2-Dimethyl-5-[(p-toluenesulfonyl)oxyimino]-1,3-dioxane-4,6-dione; Tosyloxyimino Meldrum's Acid; p-Toluenesulfonyloxyimino Meldrum's Acid; N-Hydroxy Meldrum's Acid p-Toluenesulfonate; Active Ester of Meldrum's Acid; Acylating Agent 215436-24-1
EINECS	Contact for details

Quality Control

Our 5-(Tosyloxyimino)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and industrial use. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with relevant standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.