Description

2-(6-Aminohexyl) Aminoadenosine-3',5'-Cyclic Monophosphate is a chemically modified, cell-permeable analog of cyclic adenosine monophosphate (cAMP), a crucial secondary messenger in cellular signaling. This compound is engineered for enhanced stability and membrane permeability, making it a powerful tool for pharmacological and biochemical research. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences industries to study and modulate intracellular cAMP-dependent pathways.

Application

• Biochemical Research: As a potent activator of protein kinase A (PKA) for studying cAMP-mediated signal transduction pathways.
• Pharmaceutical Development: Used in high-throughput screening and target validation for drug discovery programs focused on metabolic, cardiovascular, and neurological disorders.
• Cell Biology Studies: Investigation of cellular processes such as gene expression, ion channel function, and apoptosis regulation.
• Diagnostic Reagent Manufacturing: A key component in the formulation of assay kits for detecting and quantifying cAMP-related enzymatic activity.
• Academic Research: Fundamental research in universities and institutes exploring cellular communication and receptor biology.

Basic Information

Product Name	2-(6-Aminohexyl) Aminoadenosine-3',5'-Cyclic Monophosphate
CAS No.	214276-80-9
Molecular Formula	C16H26N8O6P
Molecular Weight	466.41 g/mol
Synonyms	6-AHA-cAMP; N6-(6-Aminohexyl)-cAMP; 2-(6-Aminohexyl)amino-cAMP; 8-(6-Aminohexylamino)adenosine-3',5'-cyclic monophosphate; 8-AHA-cAMP; cAMP, 2-(6-aminohexyl)amino-; cAMP analog, cell-permeable; Adenosine 3',5'-cyclic monophosphate, 2-(6-aminohexyl)amino-
EINECS	Contact for details

Quality Control

Our 2-(6-Aminohexyl) Aminoadenosine-3',5'-Cyclic Monophosphate is produced under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.