Description

(2S)-4,4-Dimethyl-2-Pyrrolidinemethanol is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its stereochemically defined pyrrolidine structure, which is a privileged scaffold for constructing complex molecules with specific biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and fine chemicals requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Asymmetric Catalysis Ligand Precursor: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity in product formation.
• Agrochemical Synthesis: Serves as a building block for creating advanced, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances where the (2S) configuration is critical.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	(2S)-4,4-Dimethyl-2-Pyrrolidinemethanol
CAS No.	212890-85-2
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	(2S)-(-)-4,4-Dimethyl-2-pyrrolidinemethanol; (S)-(-)-4,4-Dimethyl-2-pyrrolidinemethanol; (S)-4,4-Dimethyl-2-pyrrolidinemethanol; L-4,4-Dimethyl-2-pyrrolidinemethanol; (2S)-4,4-Dimethylpyrrolidine-2-methanol; 2-Pyrrolidinemethanol, 4,4-dimethyl-, (2S)-
EINECS	Contact for details

Quality Control

Our (2S)-4,4-Dimethyl-2-Pyrrolidinemethanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and other critical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.