Description

(1S,2S)-(-)-N,n-Di-p-Tosyl-1,2-Cyclohexanediamine is a high-purity chiral diamine derivative, valued as a critical ligand and building block in asymmetric synthesis. Its primary commercial value lies in enabling the production of enantiomerically pure pharmaceuticals and fine chemicals, where stereochemical control is paramount. This compound is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand or precursor for transition metal catalysts used in C-C and C-N bond-forming reactions.
• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric excess.
• Chiral Resolution Agent: Used to separate enantiomers of racemic mixtures via diastereomeric salt formation or as a chiral auxiliary.
• Agrochemical Synthesis: Employed in the development of enantiopure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process optimization.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances where chirality impacts biological activity or odor profile.

Basic Information

Product Name	(1S,2S)-(-)-N,n-Di-p-Tosyl-1,2-Cyclohexanediamine
CAS No.	212555-28-7
Molecular Formula	C26H30N2O4S2
Molecular Weight	498.66 g/mol
Synonyms	(1S,2S)-(-)-1,2-Diaminocyclohexane N,N'-Di-p-toluenesulfonamide; (1S,2S)-(-)-1,2-DACH-Ditosylate; (1S,2S)-(-)-Cyclohexane-1,2-diamine N,N'-bis(4-methylbenzenesulfonamide); (1S,2S)-(-)-DACH-Ts2; (1S,2S)-(-)-trans-1,2-Diaminocyclohexane N,N'-ditosylamide; (1S,2S)-(-)-N,N'-Ditosyl-1,2-diaminocyclohexane; (1S,2S)-(-)-Ts-DACH; Chiral Ditosyl Diaminocyclohexane Derivative
EINECS	Contact for details

Quality Control

Our (1S,2S)-(-)-N,n-Di-p-Tosyl-1,2-Cyclohexanediamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation. We adhere to cGMP principles where applicable, and specifications can be aligned with customer-specific requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.