Description

Biotin-Xx-Hydrazide is a high-purity, functionalized biotin derivative designed for advanced bioconjugation and labeling applications. This compound is critical for researchers and manufacturers requiring precise, stable linkages in the development of diagnostic assays, targeted drug delivery systems, and affinity purification platforms. It serves as an essential building block for biochemists and process development scientists in the pharmaceutical, biotechnology, and life science research sectors.

Application

• Bioconjugation Reagent: Used for the site-specific labeling of antibodies, proteins, peptides, and oligonucleotides via hydrazone bond formation with aldehydes and ketones.
• Diagnostic Kit Development: A key component in the manufacture of ELISA, lateral flow assays, and other immunoassays for creating detection probes.
• Affinity Chromatography: Functionalization of solid supports (e.g., agarose beads) for the purification of streptavidin/avidin-tagged biomolecules.
• Drug Delivery Systems: Enables the creation of biotinylated liposomes, nanoparticles, and polymer-drug conjugates for targeted therapy.
• Cell Surface Labeling: For tagging glycoproteins and other cell surface molecules containing oxidized carbohydrate groups in flow cytometry and microscopy.
• Chemical Biology Probes: Synthesis of activity-based probes and pull-down reagents for studying protein function and interaction networks.

Basic Information

Product Name	Biotin-Xx-Hydrazide
CAS No.	211237-33-1
Molecular Formula	C19H34N6O4S
Molecular Weight	442.58 g/mol
Synonyms	Biotin-XX-hydrazide; Biotinamidocaproyl Hydrazide; Biotin-LC-Hydrazide; (+)-Biotinyl-6-aminocaproic hydrazide; N-(5-(Hydrazinecarbonyl)pentyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; Biotinamidocaproic Hydrazide; Biotin Caproyl Hydrazide; EZ-Link Biotin-XX-Hydrazide
EINECS	Contact for details

Quality Control

Our Biotin-Xx-Hydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Solvent Residues (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.