Description

Cp-4126 (Lvt Derivative Of Gemcitabine) is a key pharmaceutical intermediate and a chemically modified derivative of the nucleoside analog Gemcitabine. This compound is of significant interest for the development of novel prodrugs and targeted therapeutic agents, particularly in oncology research. It is primarily utilized by pharmaceutical R&D teams, fine chemical manufacturers, and academic institutions engaged in advanced anticancer drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of next-generation Gemcitabine prodrugs and conjugates.
• Anticancer Research: Used in preclinical and research settings to develop novel chemotherapeutic agents with potentially improved efficacy or reduced side effects.
• Prodrug Development: Key substrate for creating lipophilic or targeted derivatives designed to enhance drug delivery and bioavailability.
• Bioconjugation: Employed in the synthesis of antibody-drug conjugates (ADCs) or other targeted delivery systems for cancer therapy.
• Chemical Biology: Utilized as a tool compound to study nucleoside metabolism and mechanisms of action in cellular models.
• Process Chemistry: Acts as a standard or reference material in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.

Basic Information

Product Name	Cp-4126 (Lvt Derivative Of Gemcitabine)
CAS No.	210829-30-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Gemcitabine LVT derivative; 4-N-(L-Valyl)-2'-deoxy-2',2'-difluorocytidine; 1-(2-Deoxy-2,2-difluoro-4-O-(2,2-dimethyl-1-oxopropoxy)-D-erythro-pentofuranosyl)-4-(valylamino)-2(1H)-pyrimidinone; CP 4126; L-Valyl gemcitabine; Gemcitabine valyl prodrug
EINECS	Contact for details

Quality Control

Our Cp-4126 is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) or as specified on the label or COA. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.