Description

4-Aminophenyl -D-Thiomannopyranoside, Hydrochloride is a specialized glycoside derivative where a thio-linked mannose sugar is conjugated to an aminophenyl group. This compound matters as a crucial biochemical tool and synthetic intermediate, particularly valued for its role in studying carbohydrate-protein interactions and enzyme inhibition. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications in glycobiology, drug discovery, and the development of novel therapeutic agents.

Application

• Glycobiology Research: Used as a substrate or inhibitor in studies of glycosidases, glycosyltransferases, and lectin binding.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex glycoconjugates and potential drug candidates.
• Diagnostic Reagent Development: Employed in the design and production of assays and sensors for detecting specific carbohydrate-binding proteins.
• Bioconjugation Chemistry: The aminophenyl group facilitates coupling reactions for labeling proteins, enzymes, or surfaces in biotechnological applications.
• Enzyme Mechanism Studies: Acts as a mechanistic probe due to the thio-glycosidic bond, which is more stable to hydrolysis than its O-glycoside counterpart.
• Chemical Biology Tool: Utilized to create affinity matrices for the purification or isolation of carbohydrate-binding proteins.

Basic Information

Product Name	4-Aminophenyl -D-Thiomannopyranoside, Hydrochloride
CAS No.	210049-19-7
Molecular Formula	C12H17NO5S • HCl
Molecular Weight	331.79 g/mol (Free base: 287.33 g/mol)
Synonyms	4-Aminophenyl 1-Thio-α-D-mannopyranoside Hydrochloride; p-Aminophenyl 1-Thio-α-D-mannopyranoside HCl; 1-Thio-α-D-mannopyranoside, 4-aminophenyl, hydrochloride; APTMP • HCl; 4-Aminophenyl α-D-thiomannoside hydrochloride; 4-Aminophenyl-α-D-thiomannopyranoside HCl
EINECS	Contact for details

Quality Control

Our 4-Aminophenyl -D-Thiomannopyranoside, Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.