Description

Norzoanthamine Hydrochloride is a high-purity, semi-synthetic derivative of the marine natural product norzoanthamine, offered as a hydrochloride salt for enhanced stability and handling. This compound is of significant interest in advanced pharmaceutical research and development due to its unique structural framework and associated biological activity profile. It serves as a critical reference standard and a key synthetic intermediate for researchers in medicinal chemistry, pharmacology, and drug discovery, particularly those investigating bone metabolism and related therapeutic areas.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for analytical method development, validation, and quality control in drug research.
• Medicinal Chemistry Research: Acts as a key intermediate or lead compound for the synthesis of novel analogs targeting osteoporosis and bone-related disorders.
• Biological Activity Screening: Employed in in vitro and in vivo studies to investigate its effects on osteoblast differentiation and bone mineral density.
• Academic & Institutional Research: Serves as a crucial reagent for universities and research institutes studying marine natural products and their therapeutic potential.
• Pre-clinical Development: Utilized in pharmacokinetic, pharmacodynamic, and toxicology studies during early-stage drug candidate evaluation.

Basic Information

Product Name	Norzoanthamine Hydrochloride
CAS No.	208171-12-4
Molecular Formula	C30H45NO6 • HCl
Molecular Weight	552.1 g/mol (approx.)
Synonyms	Norzoanthamine HCl; Nor-zoanthamine Hydrochloride; (3S,5aS,6R,7S,8S,9R,10aR,10bS,12S)-7,8,12-Trihydroxy-3,6,9-trimethyl-3,4,5,5a,6,7,8,9,10,10a,10b,11-dodecahydro-2H-cyclopenta[5,6]naphtho[1,2-f]indole-1(12bH)-one Hydrochloride; Zoanthamine Derivative Hydrochloride
EINECS	Contact for details

Quality Control

Our Norzoanthamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.