Description

n-[2-[2-[2-[(n-Biotinyl-Caproylamino)-Ethoxy)Ethoxyl]-4-[2-(Trifluoromethyl)-3H-Diazirin-3-Yl]Benzoyl]-1,3-Bis(Mannopyranosyl-4-Yloxy)-2-Propylamine is a sophisticated, multifunctional chemical probe designed for advanced biochemical research and bioconjugation. This compound matters because it integrates a photoreactive diazirine group, a biotin tag for affinity purification, and mannose sugars for targeted recognition, enabling precise cross-linking and isolation of biomolecular complexes. It is primarily needed by researchers and developers in pharmaceutical discovery, glycobiology, and proteomics who require high-purity, reliable tools for studying carbohydrate-protein interactions and cell surface labeling.

Application

• Photoaffinity Labeling Probe: For covalent cross-linking and identification of carbohydrate-binding proteins (lectins) and receptors in complex biological samples.
• Glycobiology Research: As a critical tool for studying mannose-specific interactions, cell signaling pathways, and immune response mechanisms.
• Proteomics & Target Identification: Enables the isolation and characterization of low-abundance protein targets through biotin-streptavidin affinity purification.
• Drug Discovery Platforms: Used in high-throughput screening assays to identify and validate novel drug targets involved in glycan-mediated processes.
• Bioconjugation & Chemical Biology: Serves as a versatile building block for creating customized probes and diagnostic reagents with specific targeting capabilities.
• Vaccine & Adjuvant Development: Supports research into carbohydrate-based vaccine design by probing antigen-presenting cell interactions.

Basic Information

Product Name	n-[2-[2-[2-[(n-Biotinyl-Caproylamino)-Ethoxy)Ethoxyl]-4-[2-(Trifluoromethyl)-3H-Diazirin-3-Yl]Benzoyl]-1,3-Bis(Mannopyranosyl-4-Yloxy)-2-Propylamine
CAS No.	207971-25-3
Molecular Formula	C55H78F3N7O19
Molecular Weight	1186.24 g/mol
Synonyms	Biotinylated Photoreactive Mannose Probe; Biotin-Caproyl-PEG2-3-(Trifluoromethyl)diazirin-4-yl Benzoyl-Bis(Mannosyloxy)-2-Propylamine; Photoactivatable Biotin-Mannose Conjugate; 3-(Trifluoromethyl)-3H-diazirin-4-yl Benzoyl-Bis(Mannosyloxy)-2-Propylamine Biotin Caproyl PEG2 Amide; Biotin-PEG2-4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoyl-Bis(Mannosyl)-2-Propylamine; Mannose Diazirine Biotin Probe; Glycan Photoaffinity Labeling Reagent
EINECS	Contact for details

Quality Control

Our n-[2-[2-[2-[(n-Biotinyl-Caproylamino)-Ethoxy)Ethoxyl]-4-[2-(Trifluoromethyl)-3H-Diazirin-3-Yl]Benzoyl]-1,3-Bis(Mannopyranosyl-4-Yloxy)-2-Propylamine is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, critical for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and performance specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). For long-term stability, store under inert atmosphere (argon or nitrogen) and allow vials to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.