Description

8-Hydroxyquinoline-β-D-Glucuronic Acid, Sodium Salt is a high-purity biochemical conjugate widely used as a key intermediate in advanced research and diagnostic applications. This compound is valued for its role in the synthesis of sensitive probes and substrates, particularly for enzyme activity assays. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors.

Application

• Enzyme Substrate: Critical intermediate for synthesizing fluorogenic and chromogenic substrates for glucuronidase enzymes (e.g., β-glucuronidase).
• Diagnostic Reagent Manufacturing: Used in the production of reagents for clinical diagnostics and research kits.
• Biochemical Research: Serves as a precursor in studies of drug metabolism, conjugation pathways, and enzyme kinetics.
• Pharmaceutical Intermediate: Employed in the development and synthesis of novel therapeutic agents and prodrugs.
• Cell Biology & Histochemistry: Can be used to develop probes for detecting specific enzymatic activity in cells and tissues.

Basic Information

Product Name	8-Hydroxyquinoline-β-D-Glucuronic Acid, Sodium Salt
CAS No.	207728-71-0
Molecular Formula	C₁₅H₁₅NNaO₉
Molecular Weight	376.27 g/mol
Synonyms	8-Hydroxyquinoline β-D-Glucuronide Sodium Salt; 8-HQ-Glucuronide Sodium Salt; Sodium 8-Hydroxyquinoline Glucuronate; 8-Hydroxyquinoline Glucuronic Acid Sodium Salt; β-Glucuronidase Substrate Intermediate; 8-HQ-GA Na Salt; 8-Hydroxyquinolinyl-β-D-glucopyranosiduronic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our 8-Hydroxyquinoline-β-D-Glucuronic Acid, Sodium Salt is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and diagnostic applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.