Description

D-Myo-Inositol, 3,4,5-Tris(Dihydrogen Phosphate) 1-(2S)-2-(5Z,8Z,11Z,14Z)-1-Oxo-5,8,11,14-Eicosatetraenyloxy-3-(1-Oxooctadecyl)Oxypropyl Hydrogen Phosphate is a complex, high-purity phospholipid derivative of inositol, serving as a critical synthetic intermediate and reference standard. This compound matters for its role in advanced biochemical research, particularly in the study of cell signaling pathways, lipid metabolism, and the synthesis of specialized pro-resolving mediators (SPMs). It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced life science sectors who require precise, well-characterized molecules for drug discovery and development.

Application

• Pharmaceutical Research & Development: As a key synthetic intermediate or reference standard in the development of novel therapeutics targeting inflammation and lipid-mediated signaling pathways.
• Biochemical Research: For studying the biosynthesis and function of inositol phospholipids and their derivatives in cellular processes.
• Specialized Pro-Resolving Mediator (SPM) Synthesis: As a precursor in the chemical or enzymatic synthesis of resolvins and protectins, which are crucial for inflammation resolution.
• Cell Signaling Studies: Used to investigate phosphoinositide-specific phospholipase C (PLC) pathways and other lipid-second messenger systems.
• Analytical Standard: Serves as a high-purity standard for analytical methods such as HPLC, LC-MS, and NMR in quality control and metabolic profiling.
• Academic & Institutional Research: A vital tool for universities and research institutes conducting cutting-edge research in lipidomics and molecular pharmacology.

Basic Information

Product Name	D-Myo-Inositol, 3,4,5-Tris(Dihydrogen Phosphate) 1-(2S)-2-(5Z,8Z,11Z,14Z)-1-Oxo-5,8,11,14-Eicosatetraenyloxy-3-(1-Oxooctadecyl)Oxypropyl Hydrogen Phosphate
CAS No.	205487-80-5
Molecular Formula	C47H84O19P4
Molecular Weight	1081.07 g/mol
Synonyms	1-(1-Oxo-5,8,11,14-eicosatetraenyl)-2-O-(1-oxooctadecyl)-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate); PI(3,4,5)P3 derivative (arachidonoyl/stearoyl); Phosphatidylinositol (3,4,5)-trisphosphate, 1-arachidonoyl-2-stearoyl; D-myo-Inositol, 1-[2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]oxy]-3-[(1-oxooctadecyl)oxy]propyl hydrogen phosphate] 3,4,5-tris(dihydrogen phosphate); PtdIns(3,4,5)P3 (18:0/20:4); PIP3 (18:0/20:4); L-α-Phosphatidylinositol-3,4,5-trisphosphate (Soy-Std)
EINECS	Contact for details

Quality Control

Our D-Myo-Inositol, 3,4,5-Tris(Dihydrogen Phosphate) derivative is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to meet exacting in-house standards, specifications can be aligned with client requirements for specific research or cGMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95% (Area %)
Assay (P Content)	Contact for details
Solubility	Soluble in chloroform/methanol mixtures; slightly soluble in aqueous buffers
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.