Description

Kinase (Phosphorylating), Gene Rac Protein Kinase (Rattus Norvegicus) is a highly specific, recombinant enzyme critical for catalyzing the transfer of phosphate groups to target proteins, a fundamental process in cellular signaling. This product is essential for researchers and developers in the life sciences sector who require precise tools for studying Rho GTPase signaling pathways, cell motility, and cytoskeletal dynamics. It is primarily utilized in biochemical research, high-throughput screening for drug discovery, and the development of diagnostic assays targeting kinase activity.

Application

• Biochemical Research & Pathway Analysis: Used as a key reagent for in vitro studies of Rac-mediated signal transduction, phosphorylation events, and enzyme kinetics.
• Drug Discovery & High-Throughput Screening (HTS): Serves as a target enzyme in assays designed to identify and characterize novel kinase inhibitors or activators for therapeutic development.
• Diagnostic Assay Development: Employed in the development of ELISA, fluorescence polarization (FP), or luminescence-based assays to detect and quantify kinase activity in clinical or research samples.
• Cell Signaling & Proteomics Studies: Essential for investigating the role of Rac kinase in cellular processes such as cell migration, proliferation, and apoptosis.
• Enzyme Characterization & Specificity Profiling: Used to determine substrate specificity, optimal reaction conditions, and inhibitory constants (Ki) for potential drug candidates.

Basic Information

Product Name	Kinase (Phosphorylating), Gene Rac Protein Kinase (Rattus Norvegicus)
CAS No.	205396-28-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Rac Protein Kinase; Rac-PK; Recombinant Rat Rac Kinase; Protein Kinase Rac; Rac Serine/Threonine Kinase; Gene Rac Kinase; Phosphorylating Kinase (Rac); EC 2.7.11.1 (related to protein kinase activity)
EINECS	Contact for details

Quality Control

Our recombinant kinase products are manufactured under stringent conditions to ensure high purity, specific activity, and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including SDS-PAGE for purity, activity assays to confirm enzymatic function, and endotoxin testing where applicable. Certificates of Analysis (COA) detailing purity, specific activity, buffer composition, and storage conditions are provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use. Handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	Clear, colorless solution
Purity (SDS-PAGE)	≥ 90%
Specific Activity	≥ XX units/mg (Contact for details)
Protein Concentration	XX mg/mL (Contact for details)
Buffer Composition	XX mM Tris-HCl, XX mM NaCl, XX% Glycerol, pH X.X
Identification (Activity)	Conforms (Phosphorylates specific substrate)
Endotoxin Level	< 1.0 EU/µg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.