Description

H-Arg-Lys-Gly-Asp-Ile-Lys-Ser-Tyr-Pna is a synthetic peptide sequence, also known by its CAS Registry Number 204450-29-3. This compound is a valuable research-grade biochemical tool, specifically designed as a chromogenic substrate for the study of protease and peptidase enzyme activity. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical R&D, and diagnostic assay development sectors who require high-purity, well-characterized substrates for enzymatic studies.

Application

• Protease/Peptidase Research: Serving as a specific chromogenic substrate for kinetic studies and characterization of serine proteases and other related enzymes.
• Enzyme Assay Development: A key component in the development of in vitro diagnostic assays and high-throughput screening (HTS) platforms for drug discovery.
• Biochemical Pathway Analysis: Used to investigate and elucidate specific proteolytic pathways and signaling cascades in cellular and molecular biology research.
• Pharmaceutical R&D: Employed in the identification and validation of novel enzyme inhibitors as potential therapeutic agents.
• Quality Control Testing: Can be used as a reference standard in the quality control of enzyme preparations and related biopharmaceutical products.

Basic Information

Product Name	H-Arg-Lys-Gly-Asp-Ile-Lys-Ser-Tyr-Pna
CAS No.	204450-29-3
Molecular Formula	C49H78N18O14
Molecular Weight	1095.25 g/mol
Synonyms	Arg-Lys-Gly-Asp-Ile-Lys-Ser-Tyr-p-Nitroanilide; RKGDIKSY-pNA; H-Arg-Lys-Gly-Asp-Ile-Lys-Ser-Tyr-pNA; Substrate for Protease; Chromogenic Peptide Substrate; p-Nitroanilide (pNA) Peptide; Protease Research Substrate; Peptide-pNA Conjugate
EINECS	Contact for details

Quality Control

Our H-Arg-Lys-Gly-Asp-Ile-Lys-Ser-Tyr-Pna is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to ISO 9001 quality management standards, and our processes are designed to meet the rigorous demands of the global research community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. Due to its hygroscopic (moisture-sensitive) nature, the product should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term stability, store under inert atmosphere if possible.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.