Description

Z-Gly-Ala-Pro-βna CAS NO 202001-62-5 is a synthetic, protected tetrapeptide derivative, specifically a benzylamide, widely utilized as a key building block in advanced peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It is primarily targeted at the pharmaceutical, biotechnology, and life science research sectors for applications in drug discovery, proteomics, and the development of therapeutic peptides.

Application

• Pharmaceutical Intermediate: A critical building block in the solid-phase and solution-phase synthesis of novel therapeutic peptide candidates.
• Protease Substrate Analog: Used in biochemical research to study enzyme kinetics, specificity, and inhibition, particularly for proteases like prolyl oligopeptidase.
• Peptide Library Construction: Enables the combinatorial synthesis of diverse peptide libraries for high-throughput screening in drug discovery programs.
• Bioconjugation & Labeling: Serves as a scaffold for attaching reporter molecules, tags, or linkers in the development of diagnostic tools and targeted bioconjugates.
• Academic & Institutional Research: A valuable reagent for investigating peptide structure-activity relationships (SAR) and metabolic pathways.
• Reference Standard: Employed as a chromatographic or spectroscopic standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	Z-Gly-Ala-Pro-βna
CAS No.	202001-62-5
Molecular Formula	C25H28N4O6
Molecular Weight	480.52 g/mol
Synonyms	Z-Gly-Ala-Pro-Benzylamide; N-Benzyloxycarbonyl-glycyl-alanyl-proline benzylamide; CBZ-Gly-Ala-Pro-Bzl; Z-Gly-Ala-Pro-Bzl-NH2; Benzyl N-[(benzylamino)carbonyl]-L-alanyl-L-prolylglycinate; Nα-Carbobenzoxy-glycyl-L-alanyl-L-proline benzylamide; Glycine, N-[(benzyloxy)carbonyl]-, L-alanyl-L-prolyl-, benzyl ester
EINECS	Contact for details

Quality Control

Every batch of Z-Gly-Ala-Pro-βna is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and cGMP manufacturing environments. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), chiral purity, and residual solvent levels is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.