Description

Suc-Phe-Gly-Leu-βna CAS NO 202000-07-5 is a synthetic peptide derivative, specifically a succinylated tetrapeptide amide. This compound is a crucial building block and research tool in advanced pharmaceutical development and biochemical research. It is primarily utilized by researchers and manufacturers in the fields of medicinal chemistry, proteomics, and peptide-based drug discovery. Its defined structure allows for precise study of enzyme-substrate interactions and the development of novel therapeutic agents.

Application

• Protease/Enzyme Substrate Research: Used as a specific chromogenic or fluorogenic substrate for studying the activity and inhibition of various proteolytic enzymes, such as cathepsins.
• Medicinal Chemistry & Drug Discovery: Serves as a key intermediate in the design and synthesis of peptide-based inhibitors for targeting specific disease pathways.
• Biochemical Assay Development: Employed in the development of high-throughput screening (HTS) assays to identify potential drug candidates that modulate enzyme activity.
• Academic & Institutional Research: A vital tool in university and institutional labs for fundamental research in biochemistry, cell biology, and signal transduction mechanisms.
• Pharmaceutical R&D: Used in preclinical research to model and understand disease mechanisms related to protein degradation and processing.

Basic Information

Product Name	Suc-Phe-Gly-Leu-βna
CAS No.	202000-07-5
Molecular Formula	C30H38N4O7
Molecular Weight	566.65 g/mol
Synonyms	Succinyl-Phenylalanyl-Glycyl-Leucyl-4-Nitroanilide; Suc-Phe-Gly-Leu-pNA; Suc-F-G-L-βNA; N-Succinyl-L-phenylalanyl-L-glycyl-L-leucyl-L-para-nitroanilide; Cathepsin B Substrate; Protease Substrate IV; N-Suc-Phe-Gly-Leu-pNA; Enzyme Substrate Suc-F-G-L-pNA
EINECS	Contact for details

Quality Control

Our Suc-Phe-Gly-Leu-βna is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.