Description

H-Gln-Betana Hcl CAS NO 201988-95-6 is a high-purity, protected amino acid derivative primarily used as a critical building block in advanced peptide synthesis. This compound is essential for researchers and manufacturers requiring precise molecular control to develop novel therapeutic peptides and biochemical tools. It is particularly valuable for the pharmaceutical, biotechnology, and life science research sectors where reliable, high-quality intermediates are paramount for successful R&D and production.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected glutamine derivative for the controlled elongation of peptide chains in automated synthesizers.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation & Labeling: Used in the site-specific modification of peptides and proteins for diagnostic and research applications.
• Biochemical Research: Employed as a standard or reagent in studies involving glutamine metabolism, enzyme substrates, and receptor-ligand interactions.
• Combinatorial Chemistry: A valuable building block for creating diverse peptide libraries used in drug discovery and screening.

Basic Information

Product Name	H-Gln-Betana Hcl
CAS No.	201988-95-6
Molecular Formula	C11H21N3O5 • HCl
Molecular Weight	303.76 g/mol (Free base: 267.30 g/mol)
Synonyms	H-Gln(Betana)-OH • HCl; Nα-Boc-Nγ-(tert-butyloxycarbonyl)-L-glutamine; Boc-Gln(Boc)-OH • HCl; (2S)-2-[(tert-Butoxycarbonyl)amino]-5-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid hydrochloride; Boc-L-Glutamine(Boc)-OH hydrochloride; Protected L-Glutamine derivative; Nα,Nγ-Bis-Boc-L-glutamine hydrochloride
EINECS	Contact for details

Quality Control

Our H-Gln-Betana Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically >98% by HPLC), chiral purity, and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.