Description

H-Ala-Leu-Tyr-Leu-βna is a synthetic peptide sequence of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial building block and model substrate for studying enzyme kinetics, peptide stability, and structure-activity relationships. It is primarily utilized by research institutions and pharmaceutical companies engaged in proteomics, drug discovery, and the development of novel therapeutic agents. The precise sequence offers a valuable tool for investigating specific biological interactions and metabolic pathways.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic assays, particularly for proteases like chymotrypsin or subtilisin, to study cleavage specificity and kinetics.
• Pharmaceutical Development: Acts as an intermediate or a key pharmacophore in the design and synthesis of novel peptide-based drug candidates.
• Proteomics & Peptide Mapping: Serves as a reference compound in mass spectrometry for method development and calibration in protein sequencing and identification.
• Structure-Activity Relationship (SAR) Studies: Provides a defined peptide backbone for modifying side chains to analyze their effect on biological activity and binding affinity.
• Academic Research: Employed in university laboratories for teaching advanced concepts in peptide chemistry and enzymology.
• Bioconjugation & Labeling Studies: The tyrosine residue offers a site for radioiodination or other chemical modifications for tracer and imaging applications.

Basic Information

Product Name	H-Ala-Leu-Tyr-Leu-βna
CAS No.	201985-44-6
Molecular Formula	C31H42N6O6
Molecular Weight	594.71 g/mol
Synonyms	Ala-Leu-Tyr-Leu-β-naphthylamide; H-Ala-Leu-Tyr-Leu-2-Naphthylamide; A-L-Y-L-βNA; ALYL-βNA; Peptide Substrate 201985-44-6; N-(2-Naphthyl)-L-alanyl-L-leucyl-L-tyrosyl-L-leucinamide; L-Alanyl-L-leucyl-L-tyrosyl-L-leucyl-2-naphthylamide
EINECS	Contact for details

Quality Control

Our H-Ala-Leu-Tyr-Leu-βna is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and chiral analysis to verify enantiomeric purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.