Description

Ac-Lys-Ala-βna CAS NO 201984-16-9 is a synthetic, protected tripeptide derivative, specifically an N-acetylated lysine-alanine dipeptide conjugated to a β-naphthylamine (βna) moiety. This compound serves as a crucial specialized building block and research biochemical for advanced organic synthesis and pharmaceutical development. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on peptide chemistry, protease substrate studies, and fluorescent probe design.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of more complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Protease Research: Used as a specialized substrate or inhibitor scaffold in enzymatic studies to investigate protease activity and mechanism.
• Fluorescent Probe Development: The β-naphthylamine group acts as a fluorophore, making this compound valuable for creating peptide-based diagnostic or imaging agents.
• Bioconjugation Chemistry: Employed in the design and synthesis of peptide tags and linkers for protein labeling and bioconjugation applications.
• Chemical Biology Tools: Utilized in the development of activity-based probes (ABPs) to study enzyme function in complex biological systems.
• Academic & Industrial R&D: A fundamental reagent for exploring new synthetic methodologies in peptide chemistry and medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	Ac-Lys-Ala-βna
CAS No.	201984-16-9
Molecular Formula	C22H30N4O4
Molecular Weight	414.50 g/mol
Synonyms	N-Acetyl-L-lysyl-L-alanine β-naphthylamide; Ac-Lys-Ala-2-Naphthylamide; Nα-Acetyl-Nε-(tert-butoxycarbonyl)-L-lysyl-L-alanine 2-naphthylamide; Ac-K(Boc)-A-βNA; N-Acetyl-Lys(Boc)-Ala-2-Nap; N-Acetyl-N6-(tert-butoxycarbonyl)-L-lysyl-L-alanine 2-naphthylamide; Ac-Lys(Boc)-Ala-βNA; L-Alanine, N-[N2-[N6-[(1,1-dimethylethoxy)carbonyl]-N2-acetyl-L-lysyl]-, 1-(2-naphthalenyl) ester
EINECS	Contact for details

Quality Control

Our Ac-Lys-Ala-βna is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC for purity assessment and NMR for structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.