Description

Suc-Phe-Leu-Phe-4Mβna is a specialized fluorogenic peptide substrate designed for the detection and study of protease activity. This compound is critical for biochemical research and pharmaceutical development, enabling precise enzymatic assays. It is primarily utilized by researchers and quality control laboratories in the life sciences, biotechnology, and pharmaceutical industries for investigating enzyme kinetics and screening potential therapeutic inhibitors.

Application

• Protease Activity Assays: A key fluorogenic substrate for measuring the activity of chymotrypsin-like proteases, including cathepsin G and neutrophil elastase.
• Enzyme Kinetic Studies: Used in detailed kinetic analysis to determine parameters such as Km and Vmax for target proteases.
• High-Throughput Screening (HTS): Employed in pharmaceutical discovery to screen large compound libraries for novel protease inhibitors.
• Biochemical Research: A fundamental tool for studying protease function, regulation, and role in physiological and pathological processes.
• Diagnostic Development: Serves as a core component in developing diagnostic tests for conditions involving dysregulated protease activity.
• Quality Control in Biologics: Used to monitor and validate the activity of enzyme-based biopharmaceutical products during manufacturing.

Basic Information

Product Name	Suc-Phe-Leu-Phe-4Mβna
CAS No.	201982-89-0
Molecular Formula	C35H44N4O8
Molecular Weight	648.75 g/mol
Synonyms	Suc-Phe-Leu-Phe-4-Methoxy-β-naphthylamide; N-Succinyl-Phenylalanyl-Leucyl-Phenylalanyl-4-Methoxy-2-Naphthylamide; Suc-F-L-F-4MβNA; Substrate for Cathepsin G; Substrate for Neutrophil Elastase; Fluorogenic Protease Substrate; Suc-FLF-4MβNA
EINECS	Contact for details

Quality Control

Our Suc-Phe-Leu-Phe-4Mβna is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.