Description

L-Lysyl-L-Alanine 4-Methoxy-β-Naphthylamide Hydrobromide is a specialized chromogenic peptide substrate used in enzymatic assays. This compound matters for researchers and quality control labs as it provides a highly sensitive and specific method for detecting and quantifying protease activity. Professionals in pharmaceutical development, biochemical research, and diagnostic kit manufacturing need this high-purity substrate to ensure accurate and reliable results in their analytical workflows.

Application

• Protease Activity Assays: Primary substrate for the fluorometric or colorimetric detection and kinetic study of specific proteolytic enzymes, including trypsin, plasmin, and other serine proteases.
• Biochemical Research: Used in enzyme characterization, inhibitor screening, and mechanistic studies to understand protease function and regulation.
• Pharmaceutical Development: Employed in quality control testing of biopharmaceuticals and in high-throughput screening (HTS) platforms to identify novel protease inhibitors as drug candidates.
• Diagnostic Reagents: A key component in the formulation of clinical diagnostic kits for measuring protease levels in biological samples, relevant to various disease states.
• Cell Biology & Physiology: Applied in studies of cellular processes involving proteolysis, such as apoptosis, signal transduction, and extracellular matrix remodeling.

Basic Information

Product Name	L-Lysyl-L-Alanine 4-Methoxy-β-Naphthylamide Hydrobromide
CAS No.	201930-27-0
Molecular Formula	C₂₀H₃₁BrN₄O₄
Molecular Weight	471.39 g/mol
Synonyms	L-Lysyl-L-alanine 4-methoxy-2-naphthylamide hydrobromide; L-Lys-L-Ala-4-Methoxy-β-NA·HBr; Ala-Lys-4-Methoxy-β-Naphthylamide Hydrobromide; Nα-(Nα-L-Alanyl-L-lysyl)-4-methoxy-2-naphthylamine hydrobromide; Protease Substrate; Chromogenic Peptide Substrate; 4-Methoxy-2-naphthylamide derivative of Lys-Ala
EINECS	Contact for details

Quality Control

Our L-Lysyl-L-Alanine 4-Methoxy-β-Naphthylamide Hydrobromide is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive assays. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, heat, or light may lead to decomposition and reduced assay performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Assay (on dried basis)	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.