Description

Meosuc-Ala-Ala-Pro-Met-Amc is a specialized fluorogenic peptide substrate designed for the sensitive detection and measurement of protease activity. This compound is of significant value in biochemical research and pharmaceutical development, where precise enzyme kinetics are critical. It is primarily needed by researchers and quality control laboratories in the life sciences, biotechnology, and pharmaceutical industries for studying proteolytic enzymes like methionine aminopeptidase.

Application

• Protease Activity Assays: A key fluorogenic substrate for continuous, real-time monitoring of enzymatic hydrolysis by specific proteases.
• Enzyme Kinetic Studies: Used to determine kinetic parameters (Km, Vmax) and inhibition constants (Ki) for target proteases.
• High-Throughput Screening (HTS): Employed in drug discovery campaigns to identify and characterize novel protease inhibitors.
• Biochemical Research: Fundamental tool for investigating the function, regulation, and mechanism of action of proteolytic enzymes.
• Diagnostic Development: Potential use in developing clinical assays for diseases where specific protease activity is a biomarker.
• Quality Control in Biologics: Monitoring protease activity during the production and purification of therapeutic proteins.

Basic Information

Product Name	Meosuc-Ala-Ala-Pro-Met-Amc
CAS No.	201853-55-6
Molecular Formula	C27H38N6O8S
Molecular Weight	606.69 g/mol
Synonyms	N-Methoxysuccinyl-Ala-Ala-Pro-Met-7-Amido-4-Methylcoumarin; Methoxysuccinyl-Ala-Ala-Pro-Met-AMC; MeOSuc-AAPM-AMC; Fluorogenic Substrate for Methionine Aminopeptidase; MAP Substrate; AAPM-AMC; 7-Amido-4-methylcoumarin derivative of MeOSuc-AAPM; N-(Methoxycarbonyl)-Ala-Ala-Pro-Met-AMC
EINECS	Contact for details

Quality Control

Our Meosuc-Ala-Ala-Pro-Met-Amc is produced under strict quality management systems to ensure batch-to-batch consistency and high performance in sensitive assays. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water
Functional Activity	Conforms to reference standard in enzyme assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.