Description

H-Lys-Amc Acoh is a specialized protected amino acid derivative, widely recognized as a crucial building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of pharmaceuticals and bioactive peptides. It is particularly valuable for the pharmaceutical, biotechnology, and life science research industries where precise molecular construction is paramount.

Application

• Peptide Synthesis Intermediate: A key protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Research: Used in the R&D of novel therapeutic peptides and peptidomimetics targeting various diseases.
• Bioconjugation: Serves as a precursor for creating labeled peptides or peptide-drug conjugates for diagnostic and therapeutic applications.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog for protease and peptidase research.
• API Development: Acts as a critical intermediate in the synthetic pathway of active pharmaceutical ingredients (APIs) containing lysine residues.

Basic Information

Product Name	H-Lys-Amc Acoh
CAS No.	201853-23-8
Molecular Formula	C15H21N3O4
Molecular Weight	307.35 g/mol
Synonyms	Nα-Acetyl-Nε-(7-methoxycoumarin-4-yl)acetyl-L-lysine; Ac-Lys(AMC)-OH; L-Lysine, N2-acetyl-N6-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-; AMC-labeled Lysine derivative; Fluorogenic lysine derivative; Peptide synthesis building block Fmoc-Lys(AMC)-OH precursor
EINECS	Contact for details

Quality Control

Our H-Lys-Amc Acoh is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure enantiomeric purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee consistency and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.