Description

(1S,2S)-4-Methoxybenzyl 2-((S)-4-((9H-Xanthen-9-Yl)Methyl)-1-(4-Methoxybenzyl)-2,5-Dioxoimidazolidin-4-Yl)Cyclopropanecarboxylate is a sophisticated chiral building block and protected amino acid derivative of significant interest in advanced organic synthesis. Its complex, multi-functional structure makes it a critical intermediate for constructing peptide mimetics and other biologically active molecules with high stereochemical fidelity. This compound is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the development of novel therapeutics and complex chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based drugs and protease inhibitors.
• Peptidomimetic Synthesis: Used to introduce constrained cyclopropane and protected imidazolidinedione motifs into peptide backbones to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a valuable starting material or intermediate in stereoselective synthesis routes due to its defined (S,S,S) configuration.
• Chemical Biology Research: Employed in the design and synthesis of activity-based probes and molecular tools for studying enzyme function.
• Advanced Material Precursor: Potential use in creating specialized polymers or dendrimers with specific chiral and functional properties.

Basic Information

Product Name	(1S,2S)-4-Methoxybenzyl 2-((S)-4-((9H-Xanthen-9-Yl)Methyl)-1-(4-Methoxybenzyl)-2,5-Dioxoimidazolidin-4-Yl)Cyclopropanecarboxylate
CAS No.	201851-13-0
Molecular Formula	C38H36N2O6
Molecular Weight	616.71 g/mol
Synonyms	(1S,2S)-4-Methoxybenzyl 2-[(4S)-4-[(9H-xanthen-9-yl)methyl]-1-[(4-methoxyphenyl)methyl]-2,5-dioxoimidazolidin-4-yl]cyclopropane-1-carboxylate; Fmoc-D-Hph(4-OMe)-OH cyclopropane derivative (protected); Xanthydryl-protected amino acid derivative; (S,S,S)-Xan-D-Hph(4-OMe)-O-4-MeOBzl; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(4-methoxyphenyl)-L-alanine derivative; CAS 201851-13-0; 4-Methoxybenzyl ester of a Xan-protected imidazolidinedione amino acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure high chemical and chiral purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your critical R&D and cGMP manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.