Description

H-Arg-Arg-Amc 3 Hcl is a high-purity, synthetic peptide derivative featuring a C-terminal amidated arginine residue. This compound is a critical biochemical tool and building block, valued for its role in modulating protease activity and studying specific enzymatic pathways. It is primarily utilized by research institutions and pharmaceutical developers focused on cardiovascular, neurological, and metabolic disease research. The product is supplied with full analytical documentation to ensure reproducibility and reliability in sensitive applications.

Application

• Biochemical Research: As a selective substrate or inhibitor for studying trypsin-like serine proteases, including furin and other proprotein convertases.
• Pharmaceutical Development: A key intermediate in the synthesis of peptide-based drug candidates targeting blood pressure regulation and hormonal pathways.
• Protease Assay Kits: Used as a calibrated component in commercial and in-house diagnostic kits for measuring specific protease activity in biological samples.
• Cell Biology Studies: Employed to investigate intracellular protein processing, signal peptide cleavage, and receptor activation mechanisms.
• Enzyme Kinetics: Serves as a model compound for determining kinetic parameters (Km, Vmax) of arginine-specific proteolytic enzymes.
• Quality Control Reference: Acts as a certified reference standard for analytical method development and validation in QC laboratories.

Basic Information

Product Name	H-Arg-Arg-Amc 3 Hcl
CAS No.	201847-69-0
Molecular Formula	C20H40Cl3N11O3
Molecular Weight	589.96 g/mol
Synonyms	H-Arg-Arg-AMC trihydrochloride; Arg-Arg-7-Amido-4-methylcoumarin hydrochloride; Boc-Arg-Arg-AMC; L-Arginyl-L-arginine 7-amido-4-methylcoumarin trihydrochloride; Furin Substrate; Proprotein Convertase Substrate; R-R-AMC; 7-Amido-4-methylcoumarin conjugate of H-Arg-Arg-OH
EINECS	Contact for details

Quality Control

Our H-Arg-Arg-Amc 3 Hcl is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and stringent controls for residual solvents and moisture content. Certificates of Analysis (COA) detailing all test results are provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.