Description

Z-Lys-Arg-Pna 2 Hcl is a high-purity, synthetic peptide substrate used in biochemical and pharmaceutical research. This compound is critical for studying protease activity and enzyme kinetics, providing researchers with a reliable tool for mechanistic investigations. It is primarily utilized by scientists and manufacturers in the fields of pharmaceutical development, proteomics, and diagnostic assay design.

Application

• Protease and Enzyme Substrate: Used as a chromogenic substrate for the study of trypsin-like serine proteases and other specific enzymes.
• Biochemical Research: Essential for kinetic assays, inhibitor screening, and determining enzyme specificity and catalytic efficiency.
• Pharmaceutical R&D: Employed in drug discovery programs targeting proteolytic pathways for conditions like thrombosis, inflammation, and cancer.
• Diagnostic Development: Serves as a key component in the development of colorimetric or fluorometric diagnostic kits for clinical testing.
• Quality Control in Biomanufacturing: Used to monitor and validate the activity of enzyme batches in biopharmaceutical production processes.

Basic Information

Product Name	Z-Lys-Arg-Pna 2 Hcl
CAS No.	201847-59-8
Molecular Formula	C27H39Cl2N9O6
Molecular Weight	656.56 g/mol
Synonyms	Benzyloxycarbonyl-L-lysyl-L-arginine 4-nitroanilide dihydrochloride; Z-Lys-Arg-pNA 2HCl; Nα-CBZ-L-lysyl-L-arginine p-nitroanilide dihydrochloride; CBZ-Lys-Arg-pNA 2HCl; Z-Lys-Arg-NA 2HCl; Substrate for trypsin-like proteases; Chromogenic peptide substrate 201847-59-8
EINECS	Contact for details

Quality Control

Our Z-Lys-Arg-Pna 2 Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and elemental analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications to ensure it meets the rigorous standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.