Description

1,2-Dimyristoyl-Sn-Glycero-3-Phosphatidyl-Rac-Glycerol, Na Salt is a high-purity, synthetic phospholipid, specifically a sodium salt of phosphatidylglycerol (PG) with defined myristoyl (C14:0) fatty acid chains. This compound is critical for creating stable, functional lipid bilayers and vesicles, serving as a key component in advanced drug delivery systems and biomimetic research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetic industries who require precise lipid chemistry for liposomal formulations, membrane studies, and diagnostic applications.

Application

• Liposomal Drug Delivery: A key excipient for formulating stable, anionic liposomes for targeted delivery of therapeutic agents, including mRNA, siRNA, and small molecule drugs.
• Biomimetic Membrane Research: Used to create model membrane systems (e.g., vesicles, supported lipid bilayers) for studying protein-lipid interactions, membrane fusion, and permeability.
• Pulmonary Surfactant Mimetics: A component in synthetic lung surfactant formulations for research into respiratory distress syndrome (RDS) treatments.
• Diagnostic Reagent Formulation: Employed in the development of lipid-based reagents for clinical diagnostics and biosensor platforms.
• Cosmetic & Dermal Formulations: Acts as a biocompatible emulsifier and skin-conditioning agent in high-end cosmetic products designed for enhanced skin barrier function.
• Cell Culture & Cryopreservation: Used as an additive in specialized cell culture media and cryoprotectant solutions to improve cell membrane integrity.

Basic Information

Product Name	1,2-Dimyristoyl-Sn-Glycero-3-Phosphatidyl-Rac-Glycerol, Na Salt
CAS No.	200880-41-7
Molecular Formula	C36H68NaO10P
Molecular Weight	714.88 g/mol
Synonyms	DMPG-Na; 1,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt; PG(14:0/14:0) Sodium Salt; Sodium 1,2-ditetradecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol); Phosphatidylglycerol (14:0) Sodium Salt; DMPG Sodium Salt; 1,2-Dimyristoylphosphatidylglycerol Sodium Salt; rac-PG(14:0/14:0) Sodium Salt
EINECS	Contact for details

Quality Control

Our 1,2-Dimyristoyl-Sn-Glycero-3-Phosphatidyl-Rac-Glycerol, Na Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and critical impurities. We adhere to relevant cGMP guidelines for excipient manufacturing, and our quality assurance protocols are designed to meet the stringent requirements of pharmaceutical development and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (Total Phospholipid Content)
Purity (TLC)	Single major spot
Fatty Acid Composition (GC)	≥ 95% Myristic Acid (C14:0)
Water Content (KF)	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.