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1,2-Dimyristoyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt CAS NO 200880-40-6
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CAS No.:200880-40-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,2-Dimyristoyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt is a high-purity synthetic phospholipid, specifically a sodium salt of phosphatidylglycerol (PG) with defined myristoyl (C14:0) fatty acid chains. This compound matters as a critical, well-defined raw material for constructing advanced lipid-based delivery systems and biomimetic membranes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetic industries who require precise lipid components for liposomal drug delivery, vaccine adjuvants, and skin-care formulations.
Application
- Liposomal Drug Delivery Systems: A key component for creating stable, anionic liposomes for encapsulating and delivering therapeutic agents, including mRNA, siRNA, and small molecule drugs.
- Biomimetic Membrane Research: Used in model membrane studies (e.g., Langmuir-Blodgett films, vesicles) to investigate lipid-protein interactions and membrane biophysics.
- Vaccine Adjuvant Development: Incorporated into lipid nanoparticle (LNP) formulations and other adjuvant systems to enhance immune responses.
- Cosmetic & Dermal Formulations: Acts as a high-performance emulsifier and skin-identical lipid in premium skincare products to improve barrier function and delivery of active ingredients.
- Diagnostic Reagents: Utilized in the preparation of calibrators, controls, and reagents for clinical diagnostics.
- Cell Culture & Biotechnology: Serves as a supplement in serum-free media and for creating lipid coatings to modulate cell growth and differentiation.
Basic Information
| Product Name | 1,2-Dimyristoyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt |
| CAS No. | 200880-40-6 |
| Molecular Formula | C34H66NaO10P |
| Molecular Weight | 688.85 g/mol |
| Synonyms | DMPG-Na; 1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; 14:0 PG Sodium Salt; Phosphatidylglycerol (14:0/14:0) sodium salt; PG(14:0/14:0) sodium salt; 1,2-Ditetradecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; DMPG; Sodium 1,2-dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) |
| EINECS | Contact for details |
Quality Control
Our 1,2-Dimyristoyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and lipid profile analysis, to ensure compliance with exacting standards suitable for pharmaceutical R&D and formulation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and reliable batch-to-batch consistency.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store desiccated at 2-8°C.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| 1,2-Dimyristoyl Isomer Content | ≥ 95.0% |
| Lyso-Impurity (HPLC) | ≤ 1.0% |
| Solvent Residues (GC) | Meets ICH guidelines |
| Water Content (KF) | ≤ 2.0% |
| Sodium Content | Theoretical ± 5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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