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1,2-Dimyristoyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt CAS NO 200880-40-6


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CAS No.:200880-40-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dimyristoyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt is a high-purity synthetic phospholipid, specifically a sodium salt of phosphatidylglycerol (PG) with defined myristoyl (C14:0) fatty acid chains. This compound matters as a critical, well-defined raw material for constructing advanced lipid-based delivery systems and biomimetic membranes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetic industries who require precise lipid components for liposomal drug delivery, vaccine adjuvants, and skin-care formulations.

Application

  • Liposomal Drug Delivery Systems: A key component for creating stable, anionic liposomes for encapsulating and delivering therapeutic agents, including mRNA, siRNA, and small molecule drugs.
  • Biomimetic Membrane Research: Used in model membrane studies (e.g., Langmuir-Blodgett films, vesicles) to investigate lipid-protein interactions and membrane biophysics.
  • Vaccine Adjuvant Development: Incorporated into lipid nanoparticle (LNP) formulations and other adjuvant systems to enhance immune responses.
  • Cosmetic & Dermal Formulations: Acts as a high-performance emulsifier and skin-identical lipid in premium skincare products to improve barrier function and delivery of active ingredients.
  • Diagnostic Reagents: Utilized in the preparation of calibrators, controls, and reagents for clinical diagnostics.
  • Cell Culture & Biotechnology: Serves as a supplement in serum-free media and for creating lipid coatings to modulate cell growth and differentiation.

Basic Information

Product Name 1,2-Dimyristoyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt
CAS No. 200880-40-6
Molecular Formula C34H66NaO10P
Molecular Weight 688.85 g/mol
Synonyms DMPG-Na; 1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; 14:0 PG Sodium Salt; Phosphatidylglycerol (14:0/14:0) sodium salt; PG(14:0/14:0) sodium salt; 1,2-Ditetradecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; DMPG; Sodium 1,2-dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol)
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Quality Control

Our 1,2-Dimyristoyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and lipid profile analysis, to ensure compliance with exacting standards suitable for pharmaceutical R&D and formulation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and reliable batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
1,2-Dimyristoyl Isomer Content ≥ 95.0%
Lyso-Impurity (HPLC) ≤ 1.0%
Solvent Residues (GC) Meets ICH guidelines
Water Content (KF) ≤ 2.0%
Sodium Content Theoretical ± 5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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