Description

Cyclohexyl[2-(2-Methylmorpholino)Ethyl]Carbodiimide Monotoluene-p-Sulphonate is a specialized carbodiimide reagent, primarily used as a highly effective coupling agent for amide bond formation in peptide synthesis and other organic transformations. Its value lies in its ability to facilitate challenging condensation reactions with high efficiency and minimal racemization, making it a critical tool for producing high-purity intermediates. This compound is essential for research and production chemists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable and high-performance reagents for complex synthesis.

Application

• Peptide Synthesis: A key coupling reagent for the formation of amide bonds between amino acids, particularly useful for sterically hindered or sensitive sequences.
• Pharmaceutical Intermediate Manufacturing: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates requiring precise amide linkages.
• Bioconjugation: Facilitates the attachment of peptides, proteins, or other molecules to carriers, surfaces, or labels for diagnostic and therapeutic applications.
• Polymer Chemistry: Employed in the synthesis of polyamides, polyurethanes, and other polymers where controlled condensation reactions are necessary.
• Organic Synthesis Research: A versatile reagent in academic and industrial R&D labs for constructing complex molecular architectures, including natural products and macrocycles.
• Agrochemical Synthesis: Used in the production of certain herbicides and fungicides that contain amide functional groups.

Basic Information

Product Name	Cyclohexyl[2-(2-Methylmorpholino)Ethyl]Carbodiimide Monotoluene-p-Sulphonate
CAS No.	29886-98-4
Molecular Formula	C21H33N3O4S
Molecular Weight	423.57 g/mol
Synonyms	CMC-Tos; Cyclohexyl[2-(2-methylmorpholino)ethyl]carbodiimide tosylate; 2-(2-Methylmorpholino)ethyl cyclohexylcarbodiimide p-toluenesulfonate; CMC-TsOH; CMC-Tosylate; Cyclohexyl[2-(2-methylmorpholino)ethyl]carbodiimide p-toluenesulfonate; CMC-Ts; (Cyclohexyl)[2-(2-methyl-4-morpholinyl)ethyl]carbodiimide 4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our Cyclohexyl[2-(2-Methylmorpholino)Ethyl]Carbodiimide Monotoluene-p-Sulphonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.