Description

Phenylthiohydantoin-(Nepsilon-Phenylthiocarbamyl)-Lysine is a specialized derivative of lysine, modified with phenylthiohydantoin and phenylthiocarbamyl groups. This compound is a critical intermediate and analytical standard in advanced peptide sequencing and protein chemistry research. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on proteomics and analytical method development.

Application

• Edman Degradation Reagent: Used as a key derivative in the sequential degradation of peptides and proteins for amino acid sequence analysis.
• Analytical Reference Standard: Serves as a high-purity standard for calibrating HPLC, LC-MS, and other chromatographic systems in proteomics laboratories.
• Biochemical Research: Employed in studies of post-translational modifications and protein structure-function relationships.
• Pharmaceutical Intermediate: Acts as a building block in the synthesis of more complex peptide-based compounds for drug discovery.
• Proteomics Reagent: Utilized in mass spectrometry-based workflows for protein identification and characterization.

Basic Information

Product Name	Phenylthiohydantoin-(Nepsilon-Phenylthiocarbamyl)-Lysine
CAS No.	29635-94-7
Molecular Formula	C20H21N3O3S2
Molecular Weight	415.53 g/mol
Synonyms	PTH-(Nε-PTC)-Lysine; Nε-(Phenylthiocarbamyl)-Lysine Phenylthiohydantoin; PTC-Lysine-PTH; Lysine, N6-[N-(phenylamino)thioxomethyl]-, 2-(phenylamino)-5-thioxo-4-imidazolidinyl ester; Edman Degradation Lysine Derivative; (S)-2-(2-Oxo-5-(phenylamino)-4-thioxoimidazolidin-1-yl)-6-(3-phenylthioureido)hexanoic acid
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin-(Nepsilon-Phenylthiocarbamyl)-Lysine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for sensitive analytical applications. All products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.